Jeff Karp, PhD

Jeff Karp, PhD, is an acclaimed mentor and biomedical engineering professor at Harvard Medical School and MIT, a Distinguished Chair at Brigham and Women’s Hospital, and a fellow of the National Academy of Inventors. He has dedicated his research to bioinspired medical problem-solving, and his lab’s technologies have led to the formation of Thirteen companies. His technologies include a tissue glue that can seal holes inside a beating heart (inspired by snails and sandcastle worms); targeted therapy for osteoarthritis, Crohn’s disease, and brain disorders; “smart needles” that automatically stop when they reach their target; a nasal spray that neutralizes pathogens; and immunotherapy approaches to annihilate cancer. Dr. Karp lives in Brookline, Massachusetts, with his wife, children, and two Cavalier King Charle’s spaniels.

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Jeff Karp, PhD: LIT: Resensitizing Our Aliveness

The natural world has provided inspiration to poets, artists, and creatives of every ilk. And that includes inventors and innovators like Dr. Jeff Karp. In this podcast, Tami Simon speaks with the renowned biomedical engineer and founder of The Karp Lab about his new book, LIT (Life Ignition Tools): Use Nature’s Playbook to Energize Your Brain, Spark Ideas, and Ignite Action, and how you yourself can turn to the natural world as an ally for problem-solving, unexpected insight, and profound transformation on a daily basis.

Enjoy this incredibly inspiring conversation exploring: The work of the “bioinspirationalist”; how sandcastle worms inspired a new approach to vascular reconstruction in humans; the LIT state and how we can open ourselves up to limitless possibilities in any situation; the pendulum swing between “dull moments” and the times we are totally lit up; the life force within everything; the importance of changing up our routines; LEB (low energy brain); the “press pause” tool of LIT; working with intention; elevating your baseline feeling of wellness and fulfillment; viewing the world through the lens of energy transfer; how we are all contributing to evolution; the practice of cycling through your senses; appreciating our interconnectedness; creating space; aligning your thoughts and actions with your core values; turning negatives into positives; finding rituals and practices to enter into the LIT state; mining the treasures of neurodiversity; and more.

Note: This episode originally aired on Sounds True One, where these special episodes of Insights at the Edge are available to watch live on video with exclusive access to Q&As with our guests. Learn more at join.soundstrue.com.

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For more information, go to michaelsingerpodcast.com.

© Sounds True Inc. Episodes: © 2025 Michael A. Singer. All Rights Reserved.

Connie Zweig: “Meeting One of the World’s Leading ...

As a new generation joins the search for understanding and meaning in our ambiguous and uncertain world, there’s a growing resurgence of interest in the Shadow—Carl Jung’s famous term for the aspects of ourselves that hide in our unconscious yet often drive behaviors we’d rather not repeat. In this podcast, Tami Simon speaks with acclaimed Jungian therapist and author Dr. Connie Zweig about her life’s mission to help us grow in self-awareness and move toward personal and collective healing by learning how to work with the Shadow. 

This aha-moment-filled conversation explores: meeting the Shadow on the spiritual path; ego formation during childhood; the concept of repression and the problem with the closet metaphor; why the Shadow hides—and when it erupts; “romancing the Shadow”; three cues to explore with respect to compulsive behaviors; “Shadow characters” and the practice of personifying aspects of the Shadow; the intergenerational aspect; engaging Shadow work at midlife; the superego; projection in relationships; sharing our secrets; money, sex, and power; shifting from a persona marriage to a Shadow marriage; the Vedanta tradition and the teaching on leshavidya, “the remains of ignorance”; the moral development missing in many spiritually advanced practitioners; illusions, idealizations, and archetypal projections; why the first reaction to meeting the Shadow is denial; Shadow projection in the politics of our times; step one: self-examination; bridging inner work and outer work wisely; how to practice “holding the tension of opposites”; cultivating nonduality in your own psychology; the “third thing” and the transcendent function; and more.

Note: This episode originally aired on Sounds True One, where these special episodes of Insights at the Edge are available to watch live on video and with exclusive access to Q&As with our guests. Learn more at join.soundstrue.com.

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For more information, go to michaelsingerpodcast.com.

© Sounds True Inc. Episodes: © 2025 Michael A. Singer. All Rights Reserved.

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